The San Francisco 49ers took their first loss of the 2025 NFL season on September 28, dropping a 26-21 matchup to the Jacksonville Jaguars at Levi’s Stadium. To make matters worse, injuries continue to pile up for San Francisco, with wide receiver Ricky Pearsall being the latest concern.
Pearsall went down in the third quarter and briefly tried to return. However, he was listed as questionable after being evaluated for a knee injury. Despite testing the knee on the sideline in hopes of rejoining the action, he ultimately decided to sit out the rest of the game.
After the 49ers’ loss, Pearsall revealed why he opted not to push through the injury.
“I was testing it out,” Pearsall said postgame (h/t 49ers Webzone). “I fell pretty hard on that one play on the sideline, trying to keep my feet in bounds, and I fell pretty hard on my knee. And I was just feeling pain and a little bit of instability, so I wasn’t trying to really mess with it.
“I was moving around. I was working with some of the trainers to try to make it feel better to go back out there. That wasn’t the case for me. I went out for one more play and felt a little bit of pain and a little bit of instability, so I just kinda shut it down from there.”
49ers Losing Ricky Pearsall Would Be Major Blow
Coach Kyle Shanahan has leaned on the second-year receiver as a vital part of the offense, particularly with playmakers like George Kittle and Brandon Aiyuk sidelined. That’s why losing Pearsall for any stretch would put even more strain on San Francisco’s attack.
Pearsall has emerged as a key contributor in the 49ers’ injury-hit wide receiver group, and general manager and president of football operations John Lynch has undoubtedly seen what the player is capable of in a bigger role.
“It’s hard to play receiver in this league; the amount of running these guys do, Ricky can just handle it,” Lynch said on September 25 with KNBR’s “Murph and Markus” (h/t NBC Sports Bay Area). “He’s got tremendous stamina, tremendous body control. He’s a very skilled route-runner — very precise.
“When the quarterback expects him to get to a certain yardage, he’s going to do that; he’s not going to cut it short. So as a result, they’re very confident in throwing it to him. Even sometimes when he is covered, he’s shown an ability to come back to the ball.”
What Will the 49ers Miss if Ricky Pearsall Is Out?
Heading into Week 4, Pearsall had recorded 16 catches for 281 yards and an average of 17.6 yards per reception. Moreover, before leaving the contest against the Jaguars, the 49ers receiver had already registered four receptions for 46 yards.
The production loss if he cannot go against the Los Angeles Rams on Thursday Night Football will be significant, as Lynch noted his excitement to see Pearsall continue his growth.
“Ricky’s playing at a really high level, and we’re grateful for that and proud of him,” Lynch added. “He’s endured so much with what happened last year, and all he’s done is continue to work, and it’s starting to really pay off for him. …”